The clinical value of amplitude-integrated electroencephalography in a historical cohort with neonatal encephalopathy: A comparison of short-term versus prolonged-period monitoring.
J Clin Neurosci
; 126: 148-153, 2024 Aug.
Article
in En
| MEDLINE
| ID: mdl-38889593
ABSTRACT
BACKGROUND:
To compare the amplitude-integrated electroencephalography (aEEG) monitoring (short-term versus prolonged-period) for neonatal seizure detection and outcome.METHODS:
The aEEG monitoring in a historical cohort (n = 88, preterm42, and term46) with neonatal encephalopathy between 2010-2022 was re-evaluated for neonatal seizures (electrographic, electro-clinical, and clinical seizures) and EEG background scoring. The cohort was dichotomized group I (short-period with 6-12 h, n = 36) and group II (prolonged-period with 24-48 h, n = 52). Both monitoring types were evaluated for the diagnostic accuracy of the "patients with seizures" and for outcome characteristics (early death as well as adverse outcomes at 12 months of age).RESULTS:
A total of 67 (76 %) neonates of the cohort were diagnosed as "patients with seizures" electrographic-only seizures in 10 (15 %), electro-clinical seizures in 22 (33 %), and clinical-only seizures in 35 (52 %). The aEEG provides the "patients with seizures" in neonates with a 36.5 % rate with both types of monitoring 17/36 (47.2 %) with short-term and 15/52 (28.8 %) with prolonged-period monitoring. The prolonged period aEEG had higher diagnostic values for seizure detection (sensitivity = 0.73 and negative predictivity value = 0.81). However, the aEEG background scores were similar for both types of aEEG monitoring, respectively (the mean ± SD 4.73 ± 2.9 versus 4.4 ± 4. p = 0.837). The aEEG scoring was correlated with the magnitude of brain injury documented with MRI, the early death, and the adverse outcome at 12 months of age.CONCLUSIONS:
Both aEEG types are valuable for monitoring the "patients with seizures" and outcome characteristics.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Seizures
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Electroencephalography
Limits:
Female
/
Humans
/
Infant
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Male
/
Newborn
Language:
En
Journal:
J Clin Neurosci
Journal subject:
NEUROLOGIA
Year:
2024
Document type:
Article
Country of publication: