Identification of Predictors for Progression of Scoliosis in Rett Syndrome.
Dev Neurorehabil
; 27(3-4): 126-133, 2024.
Article
in En
| MEDLINE
| ID: mdl-38907992
ABSTRACT
Rett syndrome is a neurodevelopmental disorder in which scoliosis is a common orthopedic complication. This explorative study aims to identify predictors for rapid progression of scoliosis in Rett syndrome to enable variable selection for future prediction model development. A univariable logistic regression model was used to identify variables that discriminate between individuals with and without rapid progression of scoliosis (>10 ∘Cobb angle/6 months) based on multi-center data. Predictors were identified using univariable logistic regression with OR (95% CI) and AUC (95% CI). Age at inclusion, Cobb angle at baseline and epilepsy have the highest discriminative ability for rapid progression of scoliosis in Rett syndrome.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Scoliosis
/
Rett Syndrome
/
Disease Progression
Limits:
Adolescent
/
Child
/
Child, preschool
/
Female
/
Humans
/
Male
Language:
En
Journal:
Dev Neurorehabil
Journal subject:
NEUROLOGIA
/
PEDIATRIA
/
REABILITACAO
Year:
2024
Document type:
Article
Affiliation country: