Modulating Inter-Muscular Coordination Patterns in the Upper Extremity Induces Changes to Inter-Muscular, Cortico-Muscular, and Cortico-Cortical Connectivity.
IEEE J Biomed Health Inform
; PP2024 Jun 24.
Article
in En
| MEDLINE
| ID: mdl-38913515
ABSTRACT
OBJECTIVE:
The changes in neural drive to muscles associated with modulation of inter-muscular coordination in the upper extremity have not yet been investigated. Such information could help elucidate the neural mechanisms behind motor skill learning.METHODS:
Six young, neurologically healthy participants underwent a six-week training protocol to decouple two synergist elbow flexor muscles as a newly learned motor skill in the isometric force generation in upward and medial directions. Concurrent electroencephalography and surface electromyography from twelve upper extremity muscles were recorded in two conditions (As-Trained & Habitual) across two assessments (Week 0 vs. Week 6). Changes to inter-muscular connectivity (IMC), functional muscle networks, cortico-muscular connectivity (CMC), cortico-cortical connectivity (CCC) as well as functional brain network controllability (FBNC) associated with the modulation of inter-muscular coordination patterns were assessed to provide a perspective on the neural mechanisms for the newly learned motor skills.RESULTS:
Significant decreases in elbow flexor IMC, CMC, and increases in CCC were observed. No significant changes were observed for FBNC.CONCLUSION:
The results of this study suggest that modulating the inter-muscular coordination of the elbow flexor muscle synergy during isometric force generation is associated with multiple yet distinct changes in functional connectivity across the central and peripheral perspectives.SIGNIFICANCE:
Understanding the neural mechanisms of modulating inter-muscular coordination patterns can help inform motor rehabilitation regimens.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Language:
En
Journal:
IEEE J Biomed Health Inform
Year:
2024
Document type:
Article