The influence of sex-specific factors on biological transformations and health outcomes in aging processes.
Biogerontology
; 2024 Jul 13.
Article
in En
| MEDLINE
| ID: mdl-39001953
ABSTRACT
The aging process demonstrates notable differences between males and females, which are key factors in disease susceptibility and lifespan. The differences in sex chromosomes are fundamental to the presence of sex bias in organisms. Moreover, sex-specific epigenetic modifications and changes in sex hormone levels impact the development of immunity differently during embryonic development and beyond. Mitochondria, telomeres, homeodynamic space, and intestinal flora are intricately connected to sex differences in aging. These elements can have diverse effects on men and women, resulting in unique biological transformations and health outcomes as they grow older. This review explores how sex interacts with these elements and shapes the aging process.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Language:
En
Journal:
Biogerontology
Journal subject:
GERIATRIA
Year:
2024
Document type:
Article
Affiliation country: