Prevalence of psychotic symptoms in mild cognitive impairment: A systematic review and meta-analysis.
Ageing Res Rev
; 100: 102431, 2024 Sep.
Article
in En
| MEDLINE
| ID: mdl-39029803
ABSTRACT
INTRODUCTION:
Neuropsychiatric symptoms may impact prognosis in individuals with mild cognitive impairment (MCI); however, data on frequency of psychotic symptoms are sparse.METHODS:
We searched MEDLINE, EMBASE, PsychoINFO from inception to June 2023. We included studies reporting patients with MCI prevalence of (delusions and/or hallucinations. Random effects model were performed to estimate the prevalence, and subgroup and meta-regression analyses were performed to explore heterogeneity.RESULTS:
Of 3145 records identified, 36 studies were included, enrolling 20,426 patients. Overall prevalence of hallucinations was 1.78â¯% (95â¯% CI, 1.17 - 2.71) and delusions 3.84â¯% (95â¯% CI, 2.71 - 5.42), both with significant heterogeneity (/2 = 90â¯%). Prevalence of hallucinations and delusions were lower when measured by NPI scales and in population-based samples.DISCUSSION:
Delusions and hallucinations occur in MCI patients at low rates. Prevalence can be partially explained by the assessment method, sample source and study heterogeneity.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Psychotic Disorders
/
Cognitive Dysfunction
/
Hallucinations
Limits:
Humans
Language:
En
Journal:
Ageing Res Rev
Journal subject:
GERIATRIA
Year:
2024
Document type:
Article
Country of publication: