Specialized metabolites of the endophyte Annulohypoxylon areolatum hosted by Aconitum carmichaelii.
Phytochemistry
; 228: 114251, 2024 Dec.
Article
in En
| MEDLINE
| ID: mdl-39178977
ABSTRACT
Seven previously undescribed compounds, including one amino acid hybrid sesquiterpene areolatol A (1), two unusual natural sesquiterpenoid skeleton areolatones A-B (2-3) and four benzo[j]fluoranthene areolaranes A-D (4-7) were characterized from Annulohypoxylon areolatum. The structures of the compounds were determined by extensive spectroscopic analysis, X-ray diffraction analysis, and ECD and NMR computational. Notably, areolatol A (1) was the first reported sesquiterpene featuring a 5/7/3-ring system and hybridized with two molecular amino acids. In addition, areolaranes A-D (4-7) were identified as possible chemophenetic markers.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Aconitum
Language:
En
Journal:
Phytochemistry
Year:
2024
Document type:
Article
Country of publication: