Cancer-associated DNA hypermethylation of Polycomb targets requires DNMT3A dual recognition of histone H2AK119 ubiquitination and the nucleosome acidic patch.
Sci Adv
; 10(35): eadp0975, 2024 Aug 30.
Article
in En
| MEDLINE
| ID: mdl-39196936
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Protein Binding
/
Histones
/
Nucleosomes
/
CpG Islands
/
DNA Methylation
/
DNA (Cytosine-5-)-Methyltransferases
/
Ubiquitination
/
DNA Methyltransferase 3A
/
Neoplasms
Limits:
Humans
Language:
En
Journal:
Sci Adv
Year:
2024
Document type:
Article
Affiliation country:
Country of publication: