Clavulanic acid biosynthesis in Streptomyces clavuligerus: gene cloning and characterization.
Gene
; 166(1): 49-55, 1995 Dec 01.
Article
in En
| MEDLINE
| ID: mdl-8529893
ABSTRACT
Seven classes of Streptomyces clavuligerus mutants defective in clavulanic acid (CLA) biosynthesis have been identified and used to clone the chromosomal DNA encoding eight CLA biosynthetic genes. The complete sequences of three and the partial sequences of two of these biosynthetic genes are reported, together with their known or predicted functions.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Streptococcus
/
Clavulanic Acids
/
Anti-Bacterial Agents
Language:
En
Journal:
Gene
Year:
1995
Document type:
Article
Affiliation country: