Elevated serum chromium in patients on total parenteral nutrition and the ionic species of contaminant chromium.
Biol Trace Elem Res
; 50(3): 221-8, 1995 Dec.
Article
in En
| MEDLINE
| ID: mdl-8962793
ABSTRACT
Chromium (Cr), an essential micronutrient required for glucose metabolism, was found in high concentrations in up to 94% of the patients on short-term total parenteral nutrition. Approximately 50% had serum levels > 10-fold of normal (upper reference value of 3.8 nmol/L), about 18% were > 20-fold, and about 2% were 40-fold higher. The major Cr contaminant was detected in the amino acid constituents, and was found to have the trivalent ionic form. Although trivalent Cr is reported to be less genotoxic, further study is required to determine the effects on cells exposed to high concentrations of this element during parenteral nutrition over an extended period of time.
Search on Google
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Chromates
/
Chromium
/
Parenteral Nutrition, Total
Limits:
Adolescent
/
Adult
/
Aged
/
Aged80
/
Female
/
Humans
/
Male
/
Middle aged
Language:
En
Journal:
Biol Trace Elem Res
Year:
1995
Document type:
Article
Affiliation country: