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CHARLSON'S COORDINITY INDEX IN SYSTEMIC LUPUS ERYTHEMATOSUS IN BRAZILIAN PATIENTS / ÍNDICE DE COMORBIDADES DE CHARLSON NO LÚPUS ERITEMATOSO SISTÊMICO EM PACIENTES BRASILEIRAS
Preprint
in Pt
| PREPRINT-SCIELO
| ID: pps-6707
Responsible library:
BR1.1
ABSTRACT
Introduction:
The Charlson comorbidities index (CCI) assesses a person's chances of survival over the next 10 years. In systemic lupus erythematosus (SLE), multiple comorbidities and complications affect patient survival. Objetive Analize the variables that influence the CCI of a group of females with SLE.Methods:
Retrospective study of medical records of 100 lupus patients for CCI, clinical, epidemiological and serological variables.Results:
No epidemiological variable interfered in CCI. Regarding clinical manifestations, patients with glomerulonephritis had a worse CCI than those without (p<0.0001) and those with central nervous system manifestations had a tendency to worse CCI (p=0.09). Patients with anti-Ro antibodies (p=0.02) and rheumatoid factor or RF (p=0.002) were associated with a lower CCI.Conclusions:
The presence of glomerulonephritis is associated with lower survival and of the anti-Ro and RF antibodies with longer survival in SLE.RESUMO
Introdução:
O índice de comorbidades de Charlson (ICC) avalia as chances de sobrevivência de uma pessoa nos próximos 10 anos. No lúpus eritematoso sistêmico (LES) múltiplas comorbidades e complicações afetam a sobrevida.Objetivo:
Verificar as variáveis ââque influenciam no ICC de um grupo de mulheres com LES.Métodos:
Estudo retrospectivo de 100 pacientes lúpicas para o ICC, variáveis ââclínicas, epidemiológicas e sorológicas.Resultados:
Nenhuma variável epidemiológica interferiu no ICC. Quanto à clínica, pacientes com glomerulonefrite tiveram pior ICC do que os sem (p<0,0001) e os com manifestações de sistema nervoso central tiveram tendência para pior ICC (p=0,09). Portadores de anticorpos anti-Ro (p=0,02) e fator reumatoide (FR; p=0,002) se associaram com ICC menor.Conclusões:
A presença de glomerulonefrite se associa com menor sobrevida, e a dos anticorpos anti-Ro e FR com maior sobrevida no LES.
Full text:
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Collection:
09-preprints
Database:
PREPRINT-SCIELO
Type of study:
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Country/Region as subject:
America do sul
/
Brasil
Language:
Pt
Year:
2023
Document type:
Preprint
