Wells' Syndrome Associated with Churg-Strauss Syndrome
Annals of Dermatology
; : 497-500, 2011.
Article
in En
| WPRIM
| ID: wpr-155738
Responsible library:
WPRO
ABSTRACT
Churg-Strauss syndrome (CSS) is a multisystem granulomatous vasculitis that is characterized by peripheral eosinophilia and the infiltration of eosinophils into systemic organs. The skin lesions of CSS consist mainly of palpable purpura and nodules. Wells' syndrome (WS) is a rare inflammatory dermatosis that is associated with recurrent granulomatous dermatitis and eosinophilia. Since these two diseases are rare, any overlap between them is very unusual. Herein, we report a patient with CSS, who initially presented a skin eruption of erythematous urticarial-plaques, vesicles, and blisters. Upon biopsy, the histology of these plaques indicated eosinophilic infiltration and "flame figures" within the dermis, which was consistent with a diagnosis of WS. Although the association between WS and CSS that was observed in our patient may be purely coincidental, it could also suggest a common pathogenetic background of these two distinct diseases, as both share several many common features.
Key words
Full text:
1
Database:
WPRIM
Main subject:
Purpura
/
Skin
/
Skin Diseases
/
Vasculitis
/
Biopsy
/
Churg-Strauss Syndrome
/
Cellulitis
/
Blister
/
Dermis
/
Dermatitis
Limits:
Humans
Language:
En
Journal:
Annals of Dermatology
Year:
2011
Document type:
Article