Successful Treatment of Interstitial Pneumonitis Induced by Leflunomide / 대한류마티스학회지
The Journal of the Korean Rheumatism Association
; : 268-273, 2007.
Article
in Ko
| WPRIM
| ID: wpr-196275
Responsible library:
WPRO
ABSTRACT
Leflunomide is a disease-modifying antirheumatic drug that has been available in Korea since 2003. Leflunomide induced interstitial pneumonitis has been reported as an adverse effect in other countries but not in Korea. A 57-year-old woman was treated with leflunomide since she had been resistant to methotrexate, hydroxychloroquine and sulfasalazine. She developed high fever, dyspnea, and non-productive cough 3 months after the administration of leflunomide. She was diagnosed leflunomide-induced interstitial pneumonitis based on history, physical, laboratory, radiologic and pathologic findings. The patient was treated by prednisolone 1 mg/kg/day with cholestyramine 24 g/day, resulting in dramatic improvement. Here we report a case of leflunomide induced pneumonitis treated successfully with high dose steroid.
Key words
Full text:
1
Database:
WPRIM
Main subject:
Pneumonia
/
Arthritis, Rheumatoid
/
Sulfasalazine
/
Prednisolone
/
Methotrexate
/
Cholestyramine Resin
/
Lung Diseases, Interstitial
/
Cough
/
Dyspnea
/
Fever
Limits:
Female
/
Humans
Country/Region as subject:
Asia
Language:
Ko
Journal:
The Journal of the Korean Rheumatism Association
Year:
2007
Document type:
Article