Diagnosis of an indistinct Leydig cell tumor by positron emission tomography-computed tomography
Obstetrics & Gynecology Science
; : 194-198, 2019.
Article
in En
| WPRIM
| ID: wpr-741748
Responsible library:
WPRO
ABSTRACT
A 51-year-old perimenopausal female patient presented with hirsutism and voice thickening which was started approximately one and a half years ago. Her initial hormone assay revealed elevated plasma testosterone, 5a-dihydrotestosterone, and dehydroepiandrosterone (DHEA) levels and therefore androgen-secreting tumor was first suspected. However, the lesion was inconspicuous on transvaginal sonography, abdominal-pelvic computed tomography (CT) scan, and pelvic magnetic resonance (MRI) imaging. Consequently, 18F-fluorodeoxyglucose (FDG) positron emission tomography-CT was performed, which localized the lesion as a focal FDG uptake within the right adnexa. Total laparoscopic hysterectomy with bilateral salpingo-oophorectomy was performed, and although visible gross mass lesions were not observed intraoperatively, pure Leydig cell tumor was pathologically confirmed within the right ovary. Plasma testosterone, 5a-dihydrotestosterone, and DHEA levels were normalized postoperatively. Clinical signs of virilization were also significantly resolved after 3-months of follow-up.
Key words
Full text:
1
Database:
WPRIM
Main subject:
Ovary
/
Plasma
/
Testosterone
/
Virilism
/
Voice
/
Follow-Up Studies
/
Dehydroepiandrosterone
/
Sertoli-Leydig Cell Tumor
/
Diagnosis
/
Electrons
Type of study:
Diagnostic_studies
/
Observational_studies
/
Prognostic_studies
Limits:
Female
/
Humans
Language:
En
Journal:
Obstetrics & Gynecology Science
Year:
2019
Document type:
Article