MicroRNA-126 inhibits the proliferation of lung cancer cell line A549
Asian Pacific Journal of Tropical Medicine
; (12): 239-242, 2015.
Article
in En
| WPRIM
| ID: wpr-820369
Responsible library:
WPRO
ABSTRACT
OBJECTIVE@#To study the role of microRNA-126 in the development of lung cancer.@*METHODS@#The biological function of microRNA-126 was detected using EdU assay and CCK-8 assay; the target gene of microRNA-126 was analyzed using real time RT-PCR and Western blot assay.@*RESULTS@#In A549 cell line, overexpression of microRNA-126 inhibits the proliferation rate; VEGF is the target gene of microRNA-126; microRNA-126 exerts its function via regulating VEGF protein level.@*CONCLUSIONS@#microRNA-126 inhibits the proliferation in A549 cell line.
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Database:
WPRIM
Language:
En
Journal:
Asian Pacific Journal of Tropical Medicine
Year:
2015
Document type:
Article