Clinical Features of EGFR Mutation Negative in Patients
with Non-small Cell Lung Cancer and Brain Metastases / 中国肺癌杂志
Chinese Journal of Lung Cancer
; (12): 43-48, 2021.
Article
in Zh
| WPRIM
| ID: wpr-880238
Responsible library:
WPRO
ABSTRACT
In addition to rare incidence of anaplastic lymphoma kinase (ALK) and c-ros oncogene 1 receptor kinase (ROS1) positive patients, patients with brain metastases of non-small cell lung cancer (NSCLC) without epidermal growth factor receptor (EGFR) sensitive mutation have no effective systemic therapy at present, and the overall prognosis is poor. Since the low blood-brain barrier permeability of chemotherapy drugs, the local treatment plays an important role in brain metastases. To understand the clinical characteristics and treatment of brain parenchymal metastases in patients with NSCLC and EGFR mutation negative, we reviewed the incidence, onset time, site, numbers, size, symptom, therapeutic effect and disease evolution in them, which can provide reference for interventional timing and local treatment technology selection of local treatment for brain parenchymal metastases.
.
Full text:
1
Database:
WPRIM
Type of study:
Prognostic_studies
Language:
Zh
Journal:
Chinese Journal of Lung Cancer
Year:
2021
Document type:
Article