Tert-butanol application and related research progress in biomedicine / 药学学报
Acta Pharmaceutica Sinica
; (12): 2513-2521, 2021.
Article
in Zh
| WPRIM
| ID: wpr-886964
Responsible library:
WPRO
ABSTRACT
italic>Tert-butanol is an organic solvent, widely used in the medical field and chemical industry. It could be characterized by high crystallization temperature and vapor pressure. It could be easily sublimed and removed during the freeze-drying process. This review mainly describes the use of tert-butanol in the lyophilized formulations of poorly soluble drugs, the lyophilization solvent of porous structure productions, and as an ice crystal growth guider. In addition, the application of tert-butanol in nano drugs and aerogels has also been reviewed, as well as the current research progress in its quality and safety.
Full text:
1
Database:
WPRIM
Language:
Zh
Journal:
Acta Pharmaceutica Sinica
Year:
2021
Document type:
Article