Formation of the Looming-evoked Innate Defensive Response during Postnatal Development in Mice / 神经科学通报·英文版
Neuroscience Bulletin
; (6): 741-752, 2022.
Article
in En
| WPRIM
| ID: wpr-939833
Responsible library:
WPRO
ABSTRACT
Environmental threats often trigger innate defensive responses in mammals. However, the gradual development of functional properties of these responses during the postnatal development stage remains unclear. Here, we report that looming stimulation in mice evoked flight behavior commencing at P14-16 and had fully developed by P20-24. The visual-evoked innate defensive response was not significantly altered by sensory deprivation at an early postnatal stage. Furthermore, the percentages of wide-field and horizontal cells in the superior colliculus were notably elevated at P20-24. Our findings define a developmental time window for the formation of the visual innate defense response during the early postnatal period and provide important insight into the underlying mechanism.
Key words
Full text:
1
Database:
WPRIM
Main subject:
Superior Colliculi
/
Evoked Potentials, Visual
/
Fear
/
Mammals
/
Mice, Inbred C57BL
/
Neurons
Limits:
Animals
Language:
En
Journal:
Neuroscience Bulletin
Year:
2022
Document type:
Article