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Prevalence and associated risk factors of Hepatitis B and C virus infections among mothers in Jimma, South West Ethiopia: a community-based study
Taye, Belayne Dimah; Kassa, Tesfaye; Teshager, Lule; Kedir, Rebie; Yeshanew, Addisu Gize; Aseffa, Abraham; Howe, Rawleigh; Mihret, Adane.
Afiliação
  • Taye, Belayne Dimah; s.af
  • Kassa, Tesfaye; s.af
  • Teshager, Lule; s.af
  • Kedir, Rebie; s.af
  • Yeshanew, Addisu Gize; s.af
  • Aseffa, Abraham; s.af
  • Howe, Rawleigh; s.af
  • Mihret, Adane; s.af
Ethiop. med. j. (Online) ; 57(3): 109-117, 2019. tab
Artigo em Inglês | AIM (África) | ID: biblio-1262020
Biblioteca responsável: CG1.1
ABSTRACT

Background:

Viral hepatitis affects over 400 million people globally with 6 to 10 million people newly infected each year. Viral hepatitis infectious agents such as hepatitis B virus (HBV) and hepatitis C virus (HCV) are among the greatest threats to the liver and can cause liver cancer. One of the most important modes of transmission of these viruses is a vertical transmission from mother to child. The aim of this study is to assess the prevalence of HBV and HCV infection as well as its associated risk factors among mothers in Jimma.

Methods:

A community-based cross-sectional study was conducted among 455 mothers in Jimma from June to December 2016. Simple random sampling was employed to recruit study participants and informed consent was obtained. From each mother, about 5ml of blood was collected and tested for HBsAg, anti-HBc, and HCVAg/Ab using ELISA. Chi-square and logistic regression tests were used to assess statistically significant associations between dependent and independent variables. P-values less than 0.05 were considered statistically significant.

Result:

HBsAg, anti-HBc and HCVAg/Ab prevalence was 5.7%, 30.5% and 2.5%, respectively. Multivariate logis-ic regression analysis showed that history of hospital admission (AOR = 3.098; P <0.040) and abortion (AOR = 15.514, P <0.001) remained independent predictors of HBsAg seropositivity.

Conclusion:

Hospital admission and abortion are the major risk factors for hepatitis B and C virus infection among mothers. Awareness creation for adult HBV vaccine and health education on modes of transmission should be promoted and strengthened
Assuntos
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Base de dados: AIM (África) Assunto principal: Vírus da Hepatite B / Aborto / Etiópia / Antígenos de Superfície da Hepatite B / Vírus de Hepatite / Mães Tipo de estudo: Estudo de etiologia / Estudo observacional / Estudo de prevalência / Estudo prognóstico / Fatores de risco País/Região como assunto: África Idioma: Inglês Revista: Ethiop. med. j. (Online) Ano de publicação: 2019 Tipo de documento: Artigo
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Base de dados: AIM (África) Assunto principal: Vírus da Hepatite B / Aborto / Etiópia / Antígenos de Superfície da Hepatite B / Vírus de Hepatite / Mães Tipo de estudo: Estudo de etiologia / Estudo observacional / Estudo de prevalência / Estudo prognóstico / Fatores de risco País/Região como assunto: África Idioma: Inglês Revista: Ethiop. med. j. (Online) Ano de publicação: 2019 Tipo de documento: Artigo
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