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Helicobacter pylori: qué debemos saber en el año 2018. Revisión de la evidencia y nuevas recomendaciones de tratamiento / Helicobacter pylori: what should we know in the year 2018. Review of the evidence and new treatment recommendations
Rev. Hosp. Clin. Univ. Chile; 30(1): 3-11, 2019. Tab., Graf.
Artigo em Espanhol | LILACS | ID: biblio-1005532
Biblioteca responsável: CL36.1
ABSTRACT
Helicobacter pylori (HP) is the most widely chronic human infection around the world, and the main risk factor for the development of gastric cancer. Our country has high rates of this neoplasia and a high prevalence of HP infection. Even both have fallen in the last year, is a major concern to diagnose the population infected with HP in early stages, before the development of premalignant lesions and properly eradicate this infection. In this review, we discussed the different methods for the diagnosis of HP and factors that change positivity as the use of proton pump inhibitors. Also, we discussed the factors to be considered in the choice of the treatment, like local resistance to antibiotics, specially clarithromycin. In the last years has been documented in Chile a significant increase in resistance to clarithromycin, from 20 to 46%, which predicts inadequate effectiveness for the classic triple therapy. As the result of the previous analysis we discussed new possible therapies, including bismuth quadruple therapy and concomitant therapy. (AU)
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Texto completo: Disponível Coleções: Bases de dados internacionais Base de dados: LILACS Assunto principal: Helicobacter pylori Tipo de estudo: Guia de prática clínica / Overview Aspecto clínico: Diagnóstico / Etiologia / Predição / Prognóstico Limite: Feminino / Humanos / Masculino Idioma: Espanhol Revista: Rev. Hosp. Clin. Univ. Chile Assunto da revista: Medicina Ano de publicação: 2019 Tipo de documento: Artigo País de afiliação: Chile Instituição/País de afiliação: Hospital Clínico Universidad de Chile/CL