Social and behavioral characteristics of male blood donors and their sexual partners: an analysis to define risk subsets
Transfusion
; 59(8): 2584-2592, Aug. 2019. tab, ilus
Artigo
em Inglês
| Sec. Est. Saúde SP, SESSP-IIERPROD, Sec. Est. Saúde SP
| ID: biblio-1016740
Biblioteca responsável:
BR31.1
Localização: BR31.1; 2019_P-016
ABSTRACT
BACKGROUND:
Men who have sex with men in Brazil are deferred from donation for 1 year since their last sexual contact. Legal proceedings in front of the Brazilian Supreme Court could compel blood collection agencies to discontinue use of sexual orientation questions.METHODS:
Data from male participants in a completed HIV risk factor case-control study were used to evaluate whether it is possible to differentiate donors at lower and higher risk for HIV using two analytical approaches latent class and random forest analyses.RESULTS:
Male blood donors were divided into three distinct risk profile classes. Class 1 includes donors who are heterosexual (96.4%), are HIV negative (88.7%), have a main partner (99.4%), and practice unprotected sex (77.8%). Class 2 Includes donors who are men who have sex with men /bisexuals' (100.0%), are HIV positive (97.4%), and were not aware of their sexual partners' HIV status (80.3%). Class 3 includes donors who are heterosexual (84.1%), practice unprotected vaginal/anal heterosexual sex (66.8% vs. 40.9%), and were both HIV positive and HIV negative (49.5% vs. 50.5%). We also found that asking donors about their partner(s)' HIV serostatus could replace asking about donors' sexual orientation and types of partners with relatively minor shifts in sensitivity (0.76 vs. 0.58), specificity (0.89 vs. 0.94), and positive predictive value (0.85 vs. 0.88).CONCLUSION:
Sexual orientation questions on the donor questionnaire could be replaced without great loss in the sensitivity, specificity, and positive predictive value. Social and sexual behaviors of donors and their partners are proxies for HIV risk and can help to develop modified questions that will need controlled trials to be validated
Texto completo:
Disponível
Coleções:
Bases de dados nacionais
/
Brasil
Base de dados:
Sec. Est. Saúde SP
/
SESSP-IIERPROD
Assunto principal:
Comportamento Sexual
/
Doadores de Sangue
/
Parceiros Sexuais
/
HIV
/
Sexo sem Proteção
Tipo de estudo:
Estudo de etiologia
/
Estudo observacional
/
Estudo prognóstico
/
Fatores de risco
Limite:
Humanos
/
Masculino
Idioma:
Inglês
Revista:
Transfusion
Ano de publicação:
2019
Tipo de documento:
Artigo
Instituição/País de afiliação:
Faculdade Ciências Médicas/BR
/
Fundacão Pró-Sangue/BR
/
Hemominas/BR
/
Hemorio/BR
/
Secretaria de Estado da Saúde. São Paulo/BR
/
Universidade Federal de Minas Gerais/BR
/
Universidade de São Paulo/BR
/
University of California/US