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Chemical constituents from ethanol extract of Polyalthia rumphii branches and their cytotoxicity evaluation
Wang, Tianshan; Wu, Xiaopeng; Liu, Yanping; Luo, Youping; Li, Xiang; Zhou, Yujie; Yang, AiPing; Yan, Zhengmeng; Ye, Ling; Chen, Siwei; Fu, Jinshuai; Jiao, Xianzhi.
Afiliação
  • Wang, Tianshan; Hainan Normal University. College of Chemistry and Chemical Engineering. Haikou. CN
  • Wu, Xiaopeng; Chinese Academy of Tropical Agricultural Science. Institute of Tropical Bioscience and Biotechnology. Haikou. CN
  • Liu, Yanping; Hainan Normal University. College of Chemistry and Chemical Engineering. Haikou. CN
  • Luo, Youping; Hainan Normal University. College of Chemistry and Chemical Engineering. Haikou. CN
  • Li, Xiang; Hainan Normal University. College of Chemistry and Chemical Engineering. Haikou. CN
  • Zhou, Yujie; Hainan Normal University. College of Chemistry and Chemical Engineering. Haikou. CN
  • Yang, AiPing; Hainan Normal University. College of Chemistry and Chemical Engineering. Haikou. CN
  • Yan, Zhengmeng; Hainan Normal University. College of Chemistry and Chemical Engineering. Haikou. CN
  • Ye, Ling; Hainan Normal University. College of Chemistry and Chemical Engineering. Haikou. CN
  • Chen, Siwei; Hainan Normal University. College of Chemistry and Chemical Engineering. Haikou. CN
  • Fu, Jinshuai; Hainan Normal University. College of Chemistry and Chemical Engineering. Haikou. CN
  • Jiao, Xianzhi; Hainan Normal University. College of Chemistry and Chemical Engineering. Haikou. CN
Rev. bras. farmacogn ; 28(2): 235-238, Mar.-Apr. 2018. tab, graf
Artigo em Inglês | LILACS | ID: biblio-1042261
Biblioteca responsável: BR1.1
ABSTRACT
ABSTRACT Twelve known compounds, including eight alkaloids, three lignans and one gossypol derivative, were isolated from the branches of Polyalthia rumphii (Blume ex Hensch.) Merr., Annonaceae. The chemical structures were determined by spectroscopic methods and comparison with literature data. All the isolates were evaluated the cytotoxicity against three human cancer cell lines Hela, MCF-7 and A549, the results showed that partial of isolates displayed weak cytotoxicities with the IC50 values ranging from 25 to 40 µg/ml.

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Texto completo: Disponível Coleções: Bases de dados internacionais Base de dados: LILACS Idioma: Inglês Revista: Rev. bras. farmacogn Assunto da revista: Farmácia Ano de publicação: 2018 Tipo de documento: Artigo País de afiliação: China Instituição/País de afiliação: Chinese Academy of Tropical Agricultural Science/CN / Hainan Normal University/CN
Texto completo
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Texto completo: Disponível Coleções: Bases de dados internacionais Base de dados: LILACS Idioma: Inglês Revista: Rev. bras. farmacogn Assunto da revista: Farmácia Ano de publicação: 2018 Tipo de documento: Artigo País de afiliação: China Instituição/País de afiliação: Chinese Academy of Tropical Agricultural Science/CN / Hainan Normal University/CN