Machine learning techniques for computer-aided classification of active inflammatory sacroiliitis in magnetic resonance imaging
Adv Rheumatol
; 60: 25, 2020. tab, graf
Artigo
em Inglês
| LILACS
| ID: biblio-1130789
Biblioteca responsável:
BR1.1
ABSTRACT
Abstract Background:
Currently, magnetic resonance imaging (MRI) is used to evaluate active inflammatory sacroiliitis related to axial spondyloarthritis (axSpA). The qualitative and semiquantitative diagnosis performed by expert radiologists and rheumatologists remains subject to significant intrapersonal and interpersonal variation. This encouraged us to use machine-learning methods for this task.Methods:
In this retrospective study including 56 sacroiliac joint MRI exams, 24 patients had positive and 32 had negative findings for inflammatory sacroiliitis according to the ASAS group criteria. The dataset was randomly split with ∼ 80% (46 samples, 20 positive and 26 negative) as training and ∼ 20% as external test (10 samples, 4 positive and 6 negative). After manual segmentation of the images by a musculoskeletal radiologist, multiple features were extracted. The classifiers used were the Support Vector Machine, the Multilayer Perceptron (MLP), and the Instance-Based Algorithm, combined with the Relief and Wrapper methods for feature selection.Results:
Based on 10-fold cross-validation using the training dataset, the MLP classifier obtained the best performance with sensitivity = 100%, specificity = 95.6% and accuracy = 84.7%, using 6 features selected by the Wrapper method. Using the test dataset (external validation) the same MLP classifier obtained sensitivity = 100%, specificity = 66.7% and accuracy = 80%.Conclusions:
Our results show the potential of machine learning methods to identify SIJ subchondral bone marrow edema in axSpA patients and are promising to aid in the detection of active inflammatory sacroiliitis on MRI STIR sequences. Multilayer Perceptron (MLP) achieved the best results.(AU)
Texto completo:
Disponível
Coleções:
Bases de dados internacionais
Base de dados:
LILACS
Assunto principal:
Imageamento por Ressonância Magnética
/
Sacroileíte
/
Aprendizado de Máquina
Tipo de estudo:
Estudo diagnóstico
/
Guia de prática clínica
/
Estudo observacional
/
Estudo prognóstico
/
Pesquisa qualitativa
Limite:
Humanos
Idioma:
Inglês
Revista:
Adv Rheumatol
Assunto da revista:
Artrite
/
Reumatologia
Ano de publicação:
2020
Tipo de documento:
Artigo
País de afiliação:
Brasil
/
Canadá
Instituição/País de afiliação:
Ribeirão Preto Medical School/BR
/
University of Calgary/CA
/
University of São Paulo/BR