Protective effect of exclusive breastfeeding and effectiveness of maternal vaccination in reducing pertussis-like illness
J. pediatr. (Rio J.)
; 97(5): 500-507, Sept.-Oct. 2021. tab
Artigo
em Inglês
| LILACS
| ID: biblio-1340155
Biblioteca responsável:
BR1.1
ABSTRACT
Abstract Objective:
To assess the protective effect of exclusive breastfeeding and the effectiveness of maternal vaccination in reducing pertussis-like illness.Method:
This was a case-control study conducted in sentinel hospitals for pertussis in Recife between July 2016 and July 2018. Cases included children aged under six months with symptoms compatible with pertussis (pertussis-like illness). Controls included children aged under six months, living in the metropolitan region of Recife with no diagnosis of pertussis-like illness and matched by the same hospital and birth date.Results:
Seventy-three cases and 194 controls were included. The diagnosis of pertussis-like illness was predominantly clinical (97,2%). Amongst the main symptoms, paroxysmal cough was observed in 95.89% of cases and vomiting in 53.4%. There were 29 hospitalized cases and no deaths. Out of the 73 cases, 47 were born to mothers vaccinated against pertussis during pregnancy, and the mothers of 144 of the 194 controls had been vaccinated. The protective effect of breastfeeding was of 74% (95% CI;38%, 89%). Children younger than six months, who were exclusively breastfed and with mothers vaccinated against pertussis during pregnancy were 5 times less likely to develop pertussis-like illness, corresponding to a protection of 79% (95% CI;31%, 94%). The effectiveness of maternal vaccination against pertussis-like illness in children under six months was low (27%) and not statistically significant (CI 95%; −34% a 60%).Conclusions:
Exclusive breastfeeding protects children under six months from pertussis-like illness and may be enhanced when associated with maternal vaccination. These strategies should be encouraged because they also protect against pertussis-like illnesses.
Texto completo:
Disponível
Coleções:
Bases de dados internacionais
Contexto em Saúde:
Agenda de Saúde Sustentável para as Américas
/
ODS3 - Saúde e Bem-Estar
/
ODS3 - Meta 3.4 Reduzir as mortes prematuras devido doenças não transmissíveis
/
ODS3 - Meta 3.2 Reduzir as mortes de recém nascidos e crianças com menos de 5 anos
Problema de saúde:
Objetivo 10: Doenças transmissíveis
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Meta 3.3: Acabar com as doenças tropicais negligenciadas e combater as doenças transmissíveis
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Meta 3.1: Reduzir a mortalidade materna
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Meta 3.4: Reduzir as mortes prematuras devido doenças não transmissíveis
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Meta 3.2: Reduzir as mortes de recém nascidos e crianças com menos de 5 anos
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Outras Doenças Respiratórias
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Infecções
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Nutrição
Base de dados:
LILACS
Assunto principal:
Aleitamento Materno
/
Coqueluche
Tipo de estudo:
Estudo observacional
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Fatores de risco
Limite:
Criança
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Feminino
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Humanos
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Lactente
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Gravidez
Idioma:
Inglês
Revista:
J. pediatr. (Rio J.)
Assunto da revista:
Pediatria
Ano de publicação:
2021
Tipo de documento:
Artigo
País de afiliação:
Brasil
Instituição/País de afiliação:
Secretaria de Saúde do Estado de Pernambuco/BR
/
Universidade de Pernambuco/BR