The effects of passive tobacco smoking on the microcirculation of the abdominal wall in rats
Acta cir. bras
; 31(11): 714-719, Nov. 2016. graf
Artigo
em Inglês
| LILACS
| ID: biblio-827665
Biblioteca responsável:
BR1.1
ABSTRACT
ABSTRACT PURPOSE:
To analysis the effects of passive smoking on the microstructure of tissues of the abdominal wall regarding microcirculation, using histopathological study of the tobacco exposed rats.METHODS:
Twenty four male Wistar rats were divided in Control Group (CG = 8 animals) and Exposition Groups (EG = 16 animals). EG was exposed to cigarette smoke 4x/day for 120 days, while CG was preserved from exposure. Food, water and housing were similar for both groups. After 120 days, urine samples were collected before necropsy to analyze cotinine levels (ng/mL) in urine and blinded histopathological analysis of the abdominal wall performed to count arteries and veins in dermal and muscular fascia layer.RESULTS:
No difference in weight was observed between both groups (P>0.05). Cotinine concentration was significantly higher in EG (P<0.05). In dermal layer, the average of vessels per animal was 8.72 (IC95% 8.31-9.13) for CG and 11,23 (IC95% 10.09-12.38) for EG. In muscular fascia layer the average of vessels per animal was 17.97 (IC95% 15.79-20.15) for CG, whereas the average for EG was of 14,85 (IC95% 12.71-17.01) (P<0.05).CONCLUSION:
Exposition to passive smoking may cause increase in the number of vessels in dermal layer, with the opposite effects at the muscular fascia layer.
Texto completo:
Disponível
Coleções:
Bases de dados internacionais
Contexto em Saúde:
ODS3 - 3A Fortalecer a implementação da estrutura da Convenção da OMS para o Controle do Tabaco
/
ODS3 - Saúde e Bem-Estar
Problema de saúde:
Proteção contra Exposição
/
Meta 3.9: Reduzir o número de mortes por produtos químicos perigosos e contaminação do ar e água do solo
Base de dados:
LILACS
Assunto principal:
Poluição por Fumaça de Tabaco
/
Fumar
/
Cotinina
/
Parede Abdominal
/
Microcirculação
Limite:
Animais
Idioma:
Inglês
Revista:
Acta cir. bras
Assunto da revista:
CIRURGIA GERAL
/
Procedimentos Cir£rgicos Operat¢rios
Ano de publicação:
2016
Tipo de documento:
Artigo
País de afiliação:
Brasil
Instituição/País de afiliação:
Universidade Federal do Rio Grande do Sul/BR