Leiomyosarcoma of the buccal mucosa: a case report / Leiomyosarcoma da mucosa bucal: relato de caso

ABSTRACT

Leiomyosarcomas account for 6 per cent to 7 per cent of soft tissues sarcomas. Their main site of occurrence is in the uterus, gastrointestinal tract, and retroperitoneum; they are extremely rare in the oral and maxillofacial region. In 1995, Izumi et al reviewed 60 examples of oral leiomyosarcoma, of which only six (10 per cent) cases occurred in the buccal mucosa. The definitive histologic diagnosis of oral leiomyosarcoma is difficult because of the similarity with other sarcomas that are composed of fascicles of moderately differentiated spindle cells. Immunohistochemical analysis for cytoskeletal proteins such as actin, vimentin, myosin, and desmin has been widely used for the diagnosis of leiomyosarcoma. The purpose of this report is to describe a case of leiomyosarcoma of the buccal mucosa and its immunohistochemical features that were useful in arriving at the final diagnosis