Study of minor salivary gland mucoepidermoid carcinoma differentiation based on immunohistochemical expression of cytokeratins, vimentin and muscle-specific actin / Estudo da diferença do carcinoma mucoepidermoide em glândula salivar menor baseado em expressão imunohistoquimica de citoqueratinas, vimentina e ação específica do músculo

ABSTRACT

The expression of cytokeratins (CKs) 7,8,10,13,14,18,19, vimentin and muscle-specific actin (MSA) was investigated in 17 mucoepidermoid carcinomas (MEC) by the streptavidin-biotin technique. The results revealed that CKs 7, 8 and 18 were positive for intermediate, luminal colummar and mucous cells. For epidermoid cells, the expression was heterogeneous and discrete. The reaction with CK 19 was similar to that seen for the above CKs, except for the fact that mucous cells were negative. CK 14 was preferentially expressed in the intermediate cells localised in basal, parabasal and epidermoid cells. CK 13 was localised in intermediate, epidermoid and luminal colummar cells. In stratifield epithelium, CK 13 was expressed in intermediate cells and negative in basal cells...