Intravenous immunoglobulin therapy among pediatric patients: labeled and off-labeled indications
Braz. J. Pharm. Sci. (Online)
; 54(1): e00008, 2018. tab
Artigo
em Inglês
| LILACS
| ID: biblio-889445
Biblioteca responsável:
BR40.1
Localização: BR40.1
ABSTRACT
ABSTRACT This study was designed to evaluate utilization patterns and clinical outcome of intravenous immunoglobulin (IVIG) therapy among pediatric patients in a tertiary hospital. Demographic data, IVIG prescribed, and clinical outcome were retrospectively reviewed from the pharmacy dispensing data and patient medical records between 2007 and 2014. One hundred and fifteen instances of IVIG administration to 108 pediatric patients were recorded. A total of 61 cases (53%) and 54 cases (47%) of the IVIG administered were for labeled and off-labeled indications, respectively. Age, weight, specialty, total IVIG usage, length of hospital stays, and mortality rate were found to be significantly associated with the indication being labeled or off-labeled (p<0.05). However, there was no significant difference in terms of adverse reactions between labeled and off-labeled indications (p>0.05). Guidelines should be developed and implemented for rational and evidence-based use of IVIG to avoid unnecessary wastage.
Texto completo:
Disponível
Coleções:
Bases de dados internacionais
Contexto em Saúde:
ODS3 - Saúde e Bem-Estar
Problema de saúde:
Meta 3.2: Reduzir as mortes de recém nascidos e crianças com menos de 5 anos
Base de dados:
LILACS
Assunto principal:
Terapêutica
/
Saúde da Criança
/
Imunoglobulinas Intravenosas
Tipo de estudo:
Guia de prática clínica
Limite:
Criança
/
Criança, pré-escolar
/
Humanos
/
Lactente
/
Recém-Nascido
Idioma:
Inglês
Revista:
Braz. J. Pharm. Sci. (Online)
Assunto da revista:
Farmacologia
/
Teraputica
/
Toxicologia
Ano de publicação:
2018
Tipo de documento:
Artigo
País de afiliação:
Malásia
Instituição/País de afiliação:
Universiti Kebangsaan Malaysia/MY