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Clinically localized type 1 and 2 papillary renal cell carcinomas have similar survival outcomes following surgery / Los carcinomas papilares de células renales tipo 1 y 2 localizados clínicamente tienen resultados de supervivencia similares después de la cirugía
Ledezma, Rodrigo A; Negron, Edris; Paner, Gladell P; Rjepaj, Chris; Lascano, Danny; Haseebuddin, Mohammed; Dangle, Pankaj; Shalhav, Arieh L; Crist, Henry; Raman, Jay D; De Castro, G. Joel; Harik, Lara; Paroder, Monika; Uzzo, Robert G; Kutikov, Alexander; Eggener, Scott E.
Afiliação
  • Ledezma, Rodrigo A; University of Chicago Medical Center. Department of Surgery. Chicago. US
  • Negron, Edris; University of Chicago Medical Center. Department of Surgery. Chicago. US
  • Paner, Gladell P; University of Chicago Medical Center. Department of Pathology. Chicago. US
  • Rjepaj, Chris; Hershey Medical Center. Penn State Milton S. US
  • Lascano, Danny; Columbia University. New York. US
  • Haseebuddin, Mohammed; Fox Chase Cancer Center Temple University Health System. Philadelphia. US
  • Dangle, Pankaj; University of Chicago Medical Center. Chicago. US
  • Shalhav, Arieh L; University of Chicago Medical Center. Chicago. US
  • Crist, Henry; Penn State Milton S. Hershey Medical Center. Department of Pathology. Hershey. US
  • Raman, Jay D; Penn State Milton S. Hershey Medical Center. Division of Urology. Hershey. US
  • De Castro, G. Joel; Columbia University. Department of Urology. New York. US
  • Harik, Lara; Columbia University. Department of Pathology. New York. US
  • Paroder, Monika; Columbia University. Department of Pathology. New York. US
  • Uzzo, Robert G; Fox Chase Cancer Center Temple University Health System. Division of Urologic Oncology. Philadelphia. US
  • Kutikov, Alexander; Fox Chase Cancer Center Temple University Health System. Division of Urologic Oncology. Philadelphia. US
  • Eggener, Scott E; University of Chicago Medical Center. Department of Urology. Chicago. US
Rev. chil. urol ; 82(1): 70-78, 2017. tab, graf
Artigo em Inglês | LILACS | ID: biblio-905895
Biblioteca responsável: CL10.1
RESUMEN
Propósito Se intentó determinar la incidencia, hallazgos patológicos, factores pronósticos y resultados clínicos para pacientes con CCR papilar clínicamente localizado. Métodos Demográfico, Se recopilaron hallazgos clínicos y patológicos en todos los pacientes con CCRP sometidos a cirugía en cuatro centros médicos académicos. El punto final primario fue la supervivencia específica del cáncer (CSS). La supervivencia sin recaída (RFS) y la supervivencia general (OS) fueron puntos finales secundarios. Kaplan- Se obtuvieron estimaciones de Meier y se usaron modelos de regresión de riesgos proporcionales de Cox para evaluar predictores de mortalidad y recaída. Resultados Identificamos 626 CCPR, de los cuales 373 (60por ciento) fueron del tipo 1 y 253 (40 por ciento) fueron del tipo 2, con tres cuartas partes de todos los tumores siendo pT1. En comparación con los pacientes con tipo 1, aquellos con tipo 2 eran mayores (edad media 63 frente a 61; (AU)
ABSTRACT
Purpose We aimed to determine incidence, pathologic fndings, prognostic factors and clinical outcomes for patients with clinically localized papillary RCC. Methods Demographic, clinical and pathologic fndings were collected on all patients with PRCC undergoing sur-gery at four academic medical centers. The primary end-point was cancer-specifc survival (CSS). Relapse-free survival (RFS) and overall survival (OS) were secondary endpoints. Kaplan­ Meier estimates were obtained, and Cox proportional hazard regression models were used to assess predictors of mortality and relapse. Results We identifed 626 PRCC, of which 373 (60 pertcent) were type 1 and 253 (40 pertcent) were type 2, with three-quar-ters of all tumors being pT1. Compared to patients with type 1, those with type 2 were older (mean age 63 vs 61; (AU)
Assuntos

Texto completo: Disponível Coleções: Bases de dados internacionais Base de dados: LILACS Assunto principal: Necrose Papilar Renal Tipo de estudo: Relato de casos Limite: Humanos Idioma: Inglês Revista: Rev. chil. urol Assunto da revista: Urologia Ano de publicação: 2017 Tipo de documento: Artigo País de afiliação: Estados Unidos Instituição/País de afiliação: Columbia University/US / Fox Chase Cancer Center Temple University Health System/US / Hershey Medical Center/US / Penn State Milton S. Hershey Medical Center/US / University of Chicago Medical Center/US

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Texto completo: Disponível Coleções: Bases de dados internacionais Base de dados: LILACS Assunto principal: Necrose Papilar Renal Tipo de estudo: Relato de casos Limite: Humanos Idioma: Inglês Revista: Rev. chil. urol Assunto da revista: Urologia Ano de publicação: 2017 Tipo de documento: Artigo País de afiliação: Estados Unidos Instituição/País de afiliação: Columbia University/US / Fox Chase Cancer Center Temple University Health System/US / Hershey Medical Center/US / Penn State Milton S. Hershey Medical Center/US / University of Chicago Medical Center/US
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