Intra uterine growth retardation in rats treated with essential oil of rosmarinus officinalis linn
Rev. interdisciplin. estud. exp. anim. hum. (impr.)
; 1(1)mar.2009.
Artigo
em Inglês
| LILACS
| ID: biblio-964301
Biblioteca responsável:
BR1.1
ABSTRACT
The essential oil of Rosmarinus officinalis L. (EORO) is used in cosmetics, in the food industry and in medicines, presenting antimicrobial and antifungal activity. Aim of the study to observe maternal toxicity and embryo development after treatment of dams with EORO. Inseminated rats were distributed in four groups (n =15) Control (C) (saline 0.5ml) and treated with 242 (T1), 484 (T2) and 968mg/Kg (T3) of EORO, from the fifth to the seventh dpc and sacrificed on the 15th dpc. Variables analyzed maternal behavior, body weight gain, food consumption, kidneys, liver and ovaries weight, hemogram, number of corpora lutea, implants, live, dead, malformed fetuses and placenta and fetuses weight. Statistics Dunnett and Chi-square tests (α=0.05). The EORO higher dose reduced (p<0.05) maternal number of erythrocytes; the haematocrit, hemoglobin concentration and the fetuses body weight. Conclusions:
Highest dose of EORO reduce the fetuse´s body weight and induced anemia in the dams.
Texto completo:
Disponível
Coleções:
Bases de dados internacionais
Base de dados:
LILACS
Assunto principal:
Rosmarinus
/
Desenvolvimento Embrionário
Tipo de estudo:
Estudo de etiologia
/
Estudo prognóstico
Limite:
Animais
Idioma:
Inglês
Revista:
Rev. interdisciplin. estud. exp. anim. hum. (impr.)
Assunto da revista:
Biologia
Ano de publicação:
2009
Tipo de documento:
Artigo
País de afiliação:
Brasil
Instituição/País de afiliação:
Juiz de Fora Federal University/BR