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The role of xanthine oxidase and the effects of antioxidants in ischemia reperfusion cell injury
Canas, Patricio E.
Afiliação
  • Canas, Patricio E; Universidad de Chile. Instituto de Nutrición y Tecnología de los Alimentos
Artigo em Inglês | BINACIS | ID: bin-14768
Biblioteca responsável: BR1.1
ABSTRACT
During last years considerable interest has been devoted to understand the role of oxugen radicals in the inschemia induced cell injury associated with reperfusion. In the brain and in others tissues, free radicals play a role as modulators of vascular tone as well as a cytotoxic role as part of the ischemia associated pathology. This review discusses methods for free radical detection in brain and in other tissues, mechanisms of radical production in the course of the ischemia reperfusion process, and the efficacy of potential antioxidant agents in post ischemia therapy, especially with respect to allopurinol, an inhibitor of xanthine oxidase, and the role of taurine and its derivatives as antioxidants in different organs including the brain. (AU)
Assuntos
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Coleções: Bases de dados nacionais / Argentina Base de dados: BINACIS Assunto principal: Xantina Oxidase / Niacinato de Xantinol / Traumatismo por Reperfusão / Inibidores Enzimáticos / Isquemia / Antioxidantes Idioma: Inglês Revista: Acta physiol. pharmacol. ther. latinoam Ano de publicação: 1999 Tipo de documento: Artigo
Buscar no Google
Coleções: Bases de dados nacionais / Argentina Base de dados: BINACIS Assunto principal: Xantina Oxidase / Niacinato de Xantinol / Traumatismo por Reperfusão / Inibidores Enzimáticos / Isquemia / Antioxidantes Idioma: Inglês Revista: Acta physiol. pharmacol. ther. latinoam Ano de publicação: 1999 Tipo de documento: Artigo
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