Effects of recombinant human erythropoietin [rHuEPo] on haemostasis in patients maintained on chronic hemodialysis

ABSTRACT

The effects of recombinant erythropoietin on Haemostasis were studied in 5 patients with end stage renal disease maintained on haemodialysis. Results showed significant shortening of the bleeding time together with an increase in the levels of both factors II and X. No changes were observed in the natural anticoagulants, Protein C, Protein S, Anti-thrombine III, and the fibrinolysis inhibitors