Biochemical effects of some natural products on normal rats and their protective effects against hyperglycemia

ABSTRACT

The effect of some plants on hepatorenal functions of normal rats as well as their protective effect against hyperglycemia were studied. Lupin, fenugreek, mulberry and nabk as well as their mixture in equal portions were fed to rats for 16 weeks. Streptozotocin [STZ] was used as a hyperglycemic agent. Blood samples were collected at zero time [before treatment] then after four, six, eight and 16 weeks from treatment and were subjected to some biochemical analyses concerning the hepatorenal functions. The results showed that there was a significant effect of these plants on decreasing blood glucose level of rats. Also, these plants exhibited a pronounced effect as protective agents against hyperglycemia which may be due to the presence of flavonoids, glycoproteins and alkaloids