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ultrastructural study of the effects of cyclophosphamide on the spermatogenic cells of the adult albino rat testis and the protective role of anti oxidants
New Egyptian Journal of Medicine [The]. 2000; 23 (1): 22-30
em Inglês | IMEMR | ID: emr-54859
Biblioteca responsável: EMRO
ABSTRACT
In this study, 30 adult male albino rats were used and divided into three groups, each included ten rats. The testis of all the rat groups was subjected to ultrastructural studies. The use of electron microscopy revealed a severe affection of seminiferous tubules of the testis of rats subjected to cyclophosphamide treatment. The disturbance of normal architecture of spermatogenic cells was noticed with a loss of the normal cytoplasmic pattern and depletion of the cellular organelles. The spermatogonia, primary spermatocytes, rounded spermatids and sertoli cells showed variable affection and cellular changes. On the other hand, spermatogenic cells of the rat testis subjected to cyclophosphamide with antioxidants showed a marked decrease in the degree of affection and some of these cells acquired a normal pattern
Assuntos
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Base de dados: IMEMR Assunto principal: Ratos / Espermatócitos / Testículo / Vitamina A / Microscopia Eletrônica / Imunossupressores / Antioxidantes Limite: Animais Idioma: Inglês Revista: New Egypt. J. Med. Ano de publicação: 2000
Buscar no Google
Base de dados: IMEMR Assunto principal: Ratos / Espermatócitos / Testículo / Vitamina A / Microscopia Eletrônica / Imunossupressores / Antioxidantes Limite: Animais Idioma: Inglês Revista: New Egypt. J. Med. Ano de publicação: 2000
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