Teoria de conjuntos aplicada al recuento de linfocitos y leucocitos: prediccion de linfocitos T CD4 de pacientes con virus de la inmunodeficiencia humana/sida / Set theory applied to white cell and lymphocyte counts: prediction of CD4T lymphocytes in patients with human immunodeficiency virus/aids

RESUMEN

Basados en la teoria de conjuntos se desarrolla una metodologia de prediccion del recuento de linfocitos T CD4 (LT-CD4) a partir del numero de leucocitos y linfocitos totales. Se aplica esta metodologia a 500 muestras provenientes de pacientes con VIH con el fin de confirmar la capacidad predictiva de la metodologia. Las triplas de datos de leucocitos/ml3, linfocitos/ml3 y (..) (AU)

ABSTRACT

Based on set theory a predictive method of LT-CD4 count was developed based on the number of white blood cells and total lymphocytes. The method was applied to 500 samples, in order to confirm the method's predictive capacity. The data triplets of WBC/ml3, lymphocytes/ml3 and CD4/¦Ìl for each patient were organized in descending order according to the number of white blood cells and separated in groups of 1.000. Triplets were organized in sets A, B, C and D, and then AUC, BUD, and their intersections were established. Finally, the elements of each group were calculated and their corresponding percentage for each group of WBC was determined. As a result it was found that five of the nine groups of WBC showed an assertive percentage of 80.39% or above, and percentages of 92.54% and 100% were obtained for groups of values below 4.000/ml3 and 3.000/ml3, respectively. Results confirm that the method can be effectively applied in a clinical setting regardless of statistical measurements, and will reduce human and economic resources (AU)