Elevated plasma level of visfatin/pre-b cell colony-enhancing factor in male oral squamous cell carcinoma patients
Med. oral patol. oral cir. bucal (Internet)
; 18(2): 180-186, mar. 2013. ilus, tab
Artigo
em Inglês
| IBECS
| ID: ibc-112383
Biblioteca responsável:
ES1.1
Localização: BNCS
ABSTRACT
Objectives:
Visfatin, also known as nicotiamide phosphoribosyltransferase or pre-B cell colony enhancing factor, is a pro-inflammatory cytokine whose serum level is increased in various cancers. In this study, we investigated whether plasma visfatin levels were altered in patients with oral squamous cell carcinoma (OSCC). The relationship between plasma visfatin levels and the pretreatment hematologic profile was also explored. StudyDesign:
Plasma visfatin concentrations were measured through ELISA in OSCC patients and control sub-Design:
Plasma visfatin concentrations were measured through ELISA in OSCC patients and control sub-design:
Plasma visfatin concentrations were measured through ELISA in OSCC patients and control subjects. A total of 51 patients with OSCC and 57 age- and body mass index (BMI)-matched control subjects were studied. All study subjects were male.Results:
Plasma visfatin was found to be elevated in patients with OSCC (7.0 ± 4.5 vs. 4.8 ± 1.9 ng/ml, p = 0.002). Multiple logistic regression analysis revealed visfatin as an independent association factor for OSCC, even after full adjustment of known biomarkers. Visfatin level was significantly correlated with white blood (..) (AU)
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Coleções:
Bases de dados nacionais
/
Espanha
Base de dados:
IBECS
Assunto principal:
Neoplasias Bucais
/
Neoplasias de Células Escamosas
/
Nicotinamida Fosforribosiltransferase
Limite:
Humanos
/
Masculino
Idioma:
Inglês
Revista:
Med. oral patol. oral cir. bucal (Internet)
Ano de publicação:
2013
Tipo de documento:
Artigo