Immunomodulatory drugs: Oral and systemic adverse effects
Med. oral patol. oral cir. bucal (Internet)
; 19(1): e24-e31, ene. 2014. tab, ilus
Artigo
em Inglês
| IBECS
| ID: ibc-118249
Biblioteca responsável:
ES1.1
Localização: BNCS
ABSTRACT
OBJECTIVES:
The main objectives are to present the different adverses effects of the immunomodulatory drugs that can impair the quality of life of the immunosupressed patients and study the impact of immunomodualtion on oral diseases. Immunomodulatory drugs have changed the treatment protocols of many diseases where immune functions play a central role, such as rheumatic diseases. Their effect on oral health has not been systematically investigated, however. StudyDESIGN:
We review current data on the new immunomodulatory drugs from the oral health perspective based on open literature search of the topic.RESULTS:
These target specific drugs appear to have less drug interactions than earlier immunomodulating medicines but have nevertheless potential side effects such as activating latent infections. There are some data showing that the new immunomodulatory drugs may also have a role in the treatment of certain oral diseases such as lichen planus or ameliorating symptoms in Sjögren's syndrome, but the results have not been overly promising.CONCLUSIONS:
In general, data are sparse of the effect of these new drugs vs. oral diseases and there are no properly powered randomized controlled trials published on this topicRESUMEN
No disponible
Texto completo:
Disponível
Coleções:
Bases de dados nacionais
/
Espanha
Base de dados:
IBECS
Assunto principal:
Fatores Imunológicos
/
Doenças da Boca
Tipo de estudo:
Ensaio clínico controlado
/
Guia de prática clínica
Aspecto:
Preferência do paciente
Limite:
Humanos
Idioma:
Inglês
Revista:
Med. oral patol. oral cir. bucal (Internet)
Ano de publicação:
2014
Tipo de documento:
Artigo
Instituição/País de afiliação:
Central Hospital/Spain
/
Complutense University of Madrid/Spain
/
Helsinki University/Finland