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Burkitt’s lymphoma of the jaws in the Amazon region of Brazil
Rebelo-Pontes, Hélder-Antônio; Abreu, Michelle-Carvalho de; Guimarães, Douglas-Magno; Andrade, Bruno-Augusto-Benevenuto de; Corrêa-Pontes, Flávia-Sirotheau; Fonseca, Felipe-Paiva; Almeida, Oslei-Paes de; Júnior, Décio-Dos-Santos-Pinto.
Afiliação
  • Rebelo-Pontes, Hélder-Antônio; Federal University of Pará. João de Barros Barreto University Hospital. s. c. s. p
  • Abreu, Michelle-Carvalho de; Federal University of Pará. João de Barros Barreto University Hospital. s. c. s. p
  • Guimarães, Douglas-Magno; Federal University of Pará. João de Barros Barreto University Hospital. s. c. s. p
  • Andrade, Bruno-Augusto-Benevenuto de; Federal University of Pará. João de Barros Barreto University Hospital. s. c. s. p
  • Corrêa-Pontes, Flávia-Sirotheau; Federal University of Pará. João de Barros Barreto University Hospital. s. c. s. p
  • Fonseca, Felipe-Paiva; State University of Campinas. Piracicaba Dental School. São Paulo. Brazil
  • Almeida, Oslei-Paes de; State University of Campinas. Piracicaba Dental School. São Paulo. Brazil
  • Júnior, Décio-Dos-Santos-Pinto; University of São Paulo. Dental School. Department of Stomatology (Oral Pathology). São Paulo. Brazil
Med. oral patol. oral cir. bucal (Internet) ; 19(1): e32-e38, ene. 2014. ilus, tab
Artigo em Inglês | IBECS | ID: ibc-118250
Biblioteca responsável: ES1.1
Localização: BNCS
ABSTRACT

OBJECTIVES:

To describe the clinicopathologic and immunohistochemical features of Burkitt's lymphoma of the jaws in 7 patients of Northern Brazil. Study

DESIGN:

Clinical data concerning gender, age, affected site, clinical presentation, symptomatology and follow-up were collected from the clinical files. Histopathology was complemented with a broad immunohistochemical panel and in situ hybridization for Epstein-Barr virus (EBV).

RESULTS:

Most of the patients were infants and 5 out of 7 were males. The mandible was affected in 5 cases and all patients also presented abdominal involvement. All cases were positive for CD45, CD20, CD79a, CD10, Bcl-6 and EBV. Ki-67 proliferative index was approximately 100%. Six patients were treated with R-CHOP (Rituximab + Cyclophosphamide, Doxorubicin, Vincristine and Prednisolone) chemotherapy, and 2 of these died of the disease. One young adult patient refused treatment and died 3 months after initial diagnosis.

CONCLUSIONS:

Burkitt's lymphoma of the jaws diagnosed in the Amazon region of Brazil present similar clinico-pathologic features to those described in endemic areas of Africa, including EBV positivity
RESUMEN
No disponible
Assuntos

Texto completo: Disponível Coleções: Bases de dados nacionais / Espanha Base de dados: IBECS Assunto principal: Neoplasias Mandibulares / Linfoma de Burkitt Limite: Humanos País/Região como assunto: América do Sul / Brasil Idioma: Inglês Revista: Med. oral patol. oral cir. bucal (Internet) Ano de publicação: 2014 Tipo de documento: Artigo Instituição/País de afiliação: Federal University of Pará/s. p / State University of Campinas/Brazil / University of São Paulo/Brazil

Texto completo: Disponível Coleções: Bases de dados nacionais / Espanha Base de dados: IBECS Assunto principal: Neoplasias Mandibulares / Linfoma de Burkitt Limite: Humanos País/Região como assunto: América do Sul / Brasil Idioma: Inglês Revista: Med. oral patol. oral cir. bucal (Internet) Ano de publicação: 2014 Tipo de documento: Artigo Instituição/País de afiliação: Federal University of Pará/s. p / State University of Campinas/Brazil / University of São Paulo/Brazil
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