Hypoglycemic and hepatoprotective activity of Rosmarinus officinalis extract in diabetic rats
J. physiol. biochem
; 69(4): 779-783, dic. 2013.
Artigo
em Inglês
| IBECS
| ID: ibc-121636
Biblioteca responsável:
ES1.1
Localização: BNCS
ABSTRACT
The present study examined the effect of water extract (200 mg/kg body weight) of Rosmarinus officinalis L. in streptozotocin (STZ)-induced diabetic rats for 21 days. The hepatoprotective effects were investigated in the liver tissues sections. There was a significant increase in serum liver biochemical parameters (aspartate aminotransferase, alanine transaminase, and alkaline phosphatase), accompanied by a significant decrease in the level of total protein and albumin in the STZ-induced rats when compared with that of the normal group. The high-dose treatment group (200 mg/kg body wt) significantly restored the elevated liver function enzymes near to normal. This study revealed that rosemary extracts exerted a hepatoprotective effect. The results indicate that the extract exhibits the protective effect on tissues and prove its potentials as an antidiabetic agent (AU)
Buscar no Google
Coleções:
Bases de dados nacionais
/
Espanha
Base de dados:
IBECS
Assunto principal:
Rosmarinus
/
Hipoglicemiantes
Limite:
Animais
Idioma:
Inglês
Revista:
J. physiol. biochem
Ano de publicação:
2013
Tipo de documento:
Artigo
Instituição/País de afiliação:
El-Azher University/Egypt
/
King Abdulaziz University/Saudi Arabia