Diagnosis and current treatment of neurological paraneoplastic syndromes
Clin. transl. oncol. (Print)
; 8(11): 796-801, nov. 2006. tab
Artigo
em Inglês
| IBECS
| ID: ibc-126235
Biblioteca responsável:
ES1.1
Localização: BNCS
ABSTRACT
Neurological paraneoplastic syndromes (NPS) affect only 0.01% of cancer patients, chiefly those affected by lung, breast, ovarian and stomach cancer. They frequently cause major disability and produce limitations in patients' daily activities; the character of the disease is irreversible. Clinical suspicion is fundamental for an early diagnosis and it must be backed up by the specification of certain antibodies both present in blood and in cerebrospinal fluid (CSF). Conventional treatments are very inefficient at the time of treating these disorders; at present, the administration of immunoglobulins, immunosuppressors, chemotherapy agents and corticoids are under study, but so far results are not promising. The aim of this review is to analyze the variety of NPS and describe the findings concerning autoimmunity and treatments used at present (AU)
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Coleções:
Bases de dados nacionais
/
Espanha
Base de dados:
IBECS
Assunto principal:
Autoanticorpos
/
Síndromes Paraneoplásicas do Sistema Nervoso
/
Doenças Autoimunes do Sistema Nervoso
/
Anticorpos Antineoplásicos
Tipo de estudo:
Estudo diagnóstico
/
Estudo de rastreamento
Limite:
Humanos
Idioma:
Inglês
Revista:
Clin. transl. oncol. (Print)
Ano de publicação:
2006
Tipo de documento:
Artigo
Instituição/País de afiliação:
General Universitary Hospital/Spain
/
University Miguel Hernández/Spain