Mutual interaction between BCL6 and miRNAs contributing to the pathogenesis of various cancers
Clin. transl. oncol. (Print)
; 17(11): 841-846, nov. 2015. tab
Artigo
em Inglês
| IBECS
| ID: ibc-143453
Biblioteca responsável:
ES1.1
Localização: BNCS
ABSTRACT
MicroRNA (miRNA), a class of non-proteincoding RNAs, plays a critical role in many cellular processes, such as invasion, proliferation and migration, and also function in disease pathology. The transcription factor and proto-oncogene B cell CLL/lymphoma 6 (BCL6) is aberrantly expressed in various cancers. An increasing body of evidence has demonstrated that miRNAs and BCL6 can target one another and mutually adjust their expression which are of great importance in the pathogenesis of various cancers. In this report, we summarize the mutual interaction between miRNAs and BCL6, which have been studied in cancers, highlighting their mechanisms and potential therapeutic targets in cancers (AU)
RESUMEN
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Coleções:
Bases de dados nacionais
/
Espanha
Base de dados:
IBECS
Assunto principal:
Linfoma não Hodgkin
/
Neoplasias da Mama
/
Linfócitos B
/
Carcinoma Hepatocelular
/
MicroRNAs
/
Proteínas Proto-Oncogênicas c-bcl-6
/
Neoplasias
Tipo de estudo:
Estudo diagnóstico
/
Estudo de etiologia
Limite:
Feminino
/
Humanos
/
Masculino
Idioma:
Inglês
Revista:
Clin. transl. oncol. (Print)
Ano de publicação:
2015
Tipo de documento:
Artigo
Instituição/País de afiliação:
Third Military Medical University/China