Fat-soluble vitamin deficiencies after bariatric surgery could be misleading if they are not appropriately adjusted / Las deficiencias de vitaminas liposolubles tras la cirugía bariátrica pueden ser perjudiciales si no se ajustan adecudadamente
Nutr. hosp
; 30(1): 118-123, jul. 2014. tab, graf
Artigo
em Inglês
| IBECS
| ID: ibc-143751
Biblioteca responsável:
ES1.1
Localização: BNCS
ABSTRACT
Objective:
To evaluate the differences in frequency of fat-soluble vitamin deficiencies if we adjust their levels by its main carriers in plasma in patients undergoing Biliopancreatic diversion (BPD) and Roux-en-Y gastric bypass (RYGB). Research Methods & Procedures We recruited 178 patients who underwent RYGB (n = 116 patients) and BPD (n = 62 patients) in a single centre. Basal data information and one-year after surgery included anthropometric measurements, fat-soluble vitamins A, E and D, retinol binding protein (RBP) and total cholesterol as carriers of vitamin A and E respectively. Continuous data were compared using T-Student and proportions using chisquare test.Results:
There was a vitamin D deficiency of 96% of all patients, 10% vitamin A deficiency and 1.2% vitamin E deficiency prior to surgery. One year after surgery, 33% of patients were vitamin A deficient but the frequency reduced to 19% when we adjusted by RBP. We found a vitamin E deficiency frequency of 0% in RYGB and 4.8% in DBP one year after surgery. However, when we adjusted the serum levels to total cholesterol, we found an increased frequency of 8.7% in RYGB group for vitamin E deficiency and 21.4% in DBP (p = 0.04).Conclusion:
We have found a different frequency of deficit for fat-soluble vitamin both in BPD and RYGB once we have adjusted for its main carriers. This is clinically relevant to prevent from overexposure and toxicity. We suggest that carrier molecules should be routinely requested when we assess fat-soluble vitamin status in patients who undergo malabsorptive procedures (AU)
Texto completo:
Disponível
Coleções:
Bases de dados nacionais
/
Espanha
Base de dados:
IBECS
Assunto principal:
Vitaminas Lipossolúveis
/
Cirurgia Bariátrica
/
Obesidade
Tipo de estudo:
Estudo diagnóstico
/
Estudo de avaliação
Limite:
Humanos
Idioma:
Inglês
Revista:
Nutr. hosp
Ano de publicação:
2014
Tipo de documento:
Artigo
Instituição/País de afiliação:
Hospital Clínico San Carlos/Spain