SEOM clinical guidelines for the management of germ cell testicular cancer (2016)
Clin. transl. oncol. (Print)
; 18(12): 1187-1196, dic. 2016. tab
Artigo
em Inglês
| IBECS
| ID: ibc-158634
Biblioteca responsável:
ES1.1
Localização: BNCS
ABSTRACT
Testicular cancer represents the most common malignancy in males aged 15-34 years and is considered a model of curable neoplasm. Maintaining success, reducing treatment burden, and focusing on survivorship are then key objectives. Inguinal orchiectomy is the first recommended maneuver that has both diagnostic and therapeutic aims. Most patients are diagnosed with stage I disease (confined to the testicle). Close surveillance and selective, short-course adjuvant chemotherapy are accepted alternatives for these cases. In patients with more advanced disease (stages II and III), 3-4 courses of cisplatin based chemotherapy (according to IGCCCG risk classification) followed by the judicious surgical removal of residual masses represent the cornerstone of therapy. Poor-risk patients and those failing a first-line therapy should be referred to specialized tertiary centers. Paclitaxel-based conventional chemotherapy and high-dose chemotherapy plus autologous hematopoietic support can cure a proportion of patients with relapsing or refractory disease (AU)
RESUMEN
No disponible
Texto completo:
Disponível
Coleções:
Bases de dados nacionais
/
Espanha
Base de dados:
IBECS
Assunto principal:
Teratoma
/
Orquiectomia
/
Seminoma
/
Germinoma
/
Estadiamento de Neoplasias
Tipo de estudo:
Estudo diagnóstico
/
Guia de prática clínica
/
Estudo prognóstico
Limite:
Adolescente
/
Adulto
/
Humanos
/
Masculino
Idioma:
Inglês
Revista:
Clin. transl. oncol. (Print)
Ano de publicação:
2016
Tipo de documento:
Artigo
Instituição/País de afiliação:
Hospital Lluis Alcanyis/Spain
/
Hospital Universitario La Paz/Spain
/
Hospital Universitario Morales Meseguer/Spain
/
Hospital Universitario Sant Joan de Reus/Spain
/
Hospital Universitario Son Espases/Spain
/
Hospital Universitario Virgen del Rocío/Spain
/
Hospital Universitario y Politécnico La Fe/Spain
/
Hospital de Sant Pau/Spain
/
Institut Català dOncologia Barcelona/Spain