Incidence and survival time trends for Spanish children and adolescents with leukaemia from 1983 to 2007
Clin. transl. oncol. (Print)
; 19(3): 301-316, mar. 2017. tab, graf
Artigo
em Inglês
| IBECS
| ID: ibc-160186
Biblioteca responsável:
ES1.1
Localização: BNCS
ABSTRACT
Objective. We have analysed incidence and survival trends of children and adolescents with leukaemia registered in Spanish population-based cancer registries during the period 1983-2007. Methods. Childhood and adolescent leukaemia cases were drawn from the 11 Spanish population-based cancer registries. For survival, registries with data for the period 1991-2005 and follow-up until 31-12-2010 were included. Overall incidence trends were evaluated using joinpoint analysis. Observed survival rates were estimated using Kaplan-Meier, and trends were tested using the log-rank test. Results. Based on 2606 cases (2274 children and 332 adolescents), the overall age-adjusted incidence rate (ASRw) of leukaemia was 47.9 cases per million child-years in children and 23.8 in adolescents. The ASRw of leukaemia increased with an annual percentage change of 9.6 % (95 % CI 2.2-17.6) until 1990 followed by a stabilisation of rates. In adolescents, incidence did not increase. Five-year survival increased from 66 % in 1991-1995 to 76 % in 2001-2005. By age, survival was dramatically lower in infants (0) and adolescents (15−19) than in the other age groups and no improvement was observed. In both children and adolescents, differences in 5-year survival rates among major subgroups of leukaemias were significant. Conclusions. The increasing incidence trends observed in childhood leukaemias during the study period were confined to the beginning of the period. Remarkable improvements in survival have been observed in Spanish children with leukaemias. However, this improvement was not observed in infants and adolescents (AU)
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Coleções:
Bases de dados nacionais
/
Espanha
Contexto em Saúde:
Agenda de Saúde Sustentável para as Américas
/
ODS3 - Saúde e Bem-Estar
Problema de saúde:
Objetivo 9: Redução de doenças não transmissíveis
/
Meta 3.4: Reduzir as mortes prematuras devido doenças não transmissíveis
Base de dados:
IBECS
Assunto principal:
Leucemia
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Ficha Clínica
/
Registros
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Sobrevivência
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Neoplasias
Tipo de estudo:
Estudo de incidência
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Estudo prognóstico
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Fatores de risco
Limite:
Adolescente
/
Criança
/
Feminino
/
Humanos
/
Masculino
País/Região como assunto:
Europa
Idioma:
Inglês
Revista:
Clin. transl. oncol. (Print)
Ano de publicação:
2017
Tipo de documento:
Artigo
Instituição/País de afiliação:
Andalusian School of Public Health/Spain
/
Aragon Government/Spain
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Autonomous Government of Catalonia/Spain
/
Basque Government/Spain
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Directorate-General of Public Health and Participation/Spain
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Foundation Society for Cancer Research and Prevention (FUNCA)/Spain
/
Generalitat Valenciana/Spain
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Health and Social Welfare Authority/Spain
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Murcia Regional Health Council/Spain
/
Navarre Public Health Institute/Spain