Your browser doesn't support javascript.
loading
An international comparison of risk factors between two regions with distinct differences in asthma prevalence
Madani, K; Vlaski, E; Rennie, DC; Sears, M; Lawson, JA.
Afiliação
  • Madani, K; University of Manitoba. Department of Surgery. Winnipeg. Canada
  • Vlaski, E; University Children's Clinic. Department of Pulmonology and Allergology. Skopje. Macedonia
  • Rennie, DC; University of Saskatchewan. College of Nursing. Saskatoon. Canada
  • Sears, M; McMaster University. Department of Medicine. Division of Respirology. Hamilton. Canada
  • Lawson, JA; University of Saskatchewan. Department of Medicine. Saskatoon. Canada
Allergol. immunopatol ; 46(4): 341-353, jul.-ago. 2018. tab
Artigo em Inglês | IBECS | ID: ibc-177865
Biblioteca responsável: ES1.1
Localização: BNCS
ABSTRACT
BACKGROUND AND

PURPOSE:

Investigation of the geographic variation in asthma prevalence can improve our understanding of asthma etiology and management. The purpose of our investigation was to compare the prevalence of asthma and wheeze among adolescents living in two distinct international regions and to investigate reasons for observed differences.

METHODS:

A cross-sectional survey of 13-14 year olds was completed in Saskatoon, Canada (n = 1200) and Skopje, Republic of Macedonia (n = 3026), as part of the International Study of Asthma and Allergies in Childhood (ISAAC) Phase 3 study. Surveys were self-completed by students following the ISAAC protocol. Multiple logistic regression models were used to investigate associations with reports of asthma and current wheeze. A mediation analysis was then completed.

RESULTS:

Asthma prevalence was much higher in Saskatoon than Skopje (21.3% vs. 1.7%) as was the prevalence of current wheeze (28.2% vs. 8.8%). Higher paracetamol (acetaminophen) use was a consistent risk factor for asthma and wheeze in both locations and showed dose-response relationships. In both countries, paracetamol use and physical activity mediated some of the association for both asthma and wheeze. In Saskatoon, among those with current wheeze, 42.6% reported ever having a diagnosis of asthma compared to 10.2% among Skopje adolescents.

CONCLUSIONS:

The results suggest that the variation in risk factors between the two locations may explain some of the differences in the prevalence of asthma and wheeze between these two study sites. However, diagnostic labeling patterns should not be ruled out as another potential explanatory factor
RESUMEN
No disponible
Assuntos
Buscar no Google
Coleções: Bases de dados nacionais / Espanha Base de dados: IBECS Assunto principal: Asma Limite: Adolescente / Feminino / Humanos / Masculino País/Região como assunto: América do Norte / Europa Idioma: Inglês Revista: Allergol. immunopatol Ano de publicação: 2018 Tipo de documento: Artigo Instituição/País de afiliação: McMaster University/Canada / University Children's Clinic/Macedonia / University of Manitoba/Canada / University of Saskatchewan/Canada
Buscar no Google
Coleções: Bases de dados nacionais / Espanha Base de dados: IBECS Assunto principal: Asma Limite: Adolescente / Feminino / Humanos / Masculino País/Região como assunto: América do Norte / Europa Idioma: Inglês Revista: Allergol. immunopatol Ano de publicação: 2018 Tipo de documento: Artigo Instituição/País de afiliação: McMaster University/Canada / University Children's Clinic/Macedonia / University of Manitoba/Canada / University of Saskatchewan/Canada
...