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Effect of a 2000-m running test on antioxidant and cytokine response in plasma and circulating cells
Carrera-Quintanar, Lucrecia; Funes, Lorena; Sánchez-Martos, Miguel; Martinez-Peinado, Pascual; Sempere, José M; Pons, Antoni; Micol, Vicente; Roche, Enrique.
Afiliação
  • Carrera-Quintanar, Lucrecia; Alicante Institute for Health and Biomedical Research (ISABIAL-FISABIO Foundation). University Miguel Hernandez. Department of Applied Biology-Nutrition. Alicante. Spain
  • Funes, Lorena; University Miguel Hernandez. Institute for Molecular and Cellular Biology. Elche. Spain
  • Sánchez-Martos, Miguel; University Miguel Hernandez. Institute for Molecular and Cellular Biology. Elche. Spain
  • Martinez-Peinado, Pascual; University of Alicante. Biotechnology Department. Immunology División. Alicante. Spain
  • Sempere, José M; University of Alicante. Biotechnology Department. Immunology División. Alicante. Spain
  • Pons, Antoni; University of Balearic Islands. Department for Basic Biology and Health Sciences. Palma de Mallorca. Spain
  • Micol, Vicente; University Miguel Hernandez. Institute for Molecular and Cellular Biology. Elche. Spain
  • Roche, Enrique; Universidad Miguel Hernández. Área de Nutrición y Bromatología. Departamento de Biología Aplicada e Instituto de Bioingeniería. Elche. Spain
J. physiol. biochem ; 73(4): 523-530, nov. 2017. tab
Artigo em Inglês | IBECS | ID: ibc-178902
Biblioteca responsável: ES1.1
Localização: BNCS
ABSTRACT
Exercise intensity usually correlates with increased oxidative stress and enhanced cytokine production. However, it is unknown if all types of exercise that induce muscle damage can cause a parallel response in the oxidation balance and cytokine production. To this end, the effect of a 2000-m running test in a group of volunteers that regularly train in aerobic routines was studied. Different circulating parameters were measured, oxidative stress markers (protein carbonyls and malondialdehyde), antioxidant enzyme activity, and cytokine levels in plasma as well as in the main circulating cells of blood samples obtained in basal conditions and after test execution. As a result, the test caused muscle damage evidenced by an increase in circulating creatine kinase and myoglobin. This was accompanied by an increase in protein carbonyls in plasma and peripheral blood mononuclear cells. Activities of antioxidant enzymes (catalase, glutathione peroxidase and reductase, superoxide dismutase) were elevated in peripheral blood mononuclear cells, neutrophils, and erythrocytes after the test. Regarding cytokine production, interleukin-6, interleukin-8, interleukin-10, and tumor necrosis factor-α exhibited no significant changes after the test. Results suggest that this short but intense running exercise (2000 m) can induce muscle damage and elicit a good balance between oxidant/antioxidant responses with no changes in the circulating concentration of pro-inflammatory cytokines
Assuntos
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Coleções: Bases de dados nacionais / Espanha Base de dados: IBECS Assunto principal: Corrida / Citocinas / Antioxidantes Limite: Humanos / Masculino Idioma: Inglês Revista: J. physiol. biochem Ano de publicação: 2017 Tipo de documento: Artigo Instituição/País de afiliação: Alicante Institute for Health and Biomedical Research (ISABIAL-FISABIO Foundation)/Spain / Universidad Miguel Hernández/Spain / University Miguel Hernandez/Spain / University of Alicante/Spain / University of Balearic Islands/Spain
Buscar no Google
Coleções: Bases de dados nacionais / Espanha Base de dados: IBECS Assunto principal: Corrida / Citocinas / Antioxidantes Limite: Humanos / Masculino Idioma: Inglês Revista: J. physiol. biochem Ano de publicação: 2017 Tipo de documento: Artigo Instituição/País de afiliação: Alicante Institute for Health and Biomedical Research (ISABIAL-FISABIO Foundation)/Spain / Universidad Miguel Hernández/Spain / University Miguel Hernandez/Spain / University of Alicante/Spain / University of Balearic Islands/Spain
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