Evaluation of organ function in patients with severe COVID-19 infections / Evaluación de la función del órgano en pacientes con infección grave por COVID-19
Med. clín (Ed. impr.)
; 155(5): 191-196, sept. 2020. tab, graf
Artigo
em Inglês
| IBECS
| ID: ibc-190153
Biblioteca responsável:
ES1.1
Localização: BNCS
RESUMEN
OBJECTIVE:
The purpose of our study was to assess organ function in 102 patients with severe COVID-19 infections, using retrospective clinical analysis. MATERIAL ANDMETHODS:
A retrospective analysis was conducted on 102 patients with severe COVID-19 infections. The patients were divided into a survival group (n = 73) and a non-survival group (n = 29) according to their prognosis. The age, sex, underlying diseases, clinical laboratory data within 48 h (routine blood tests, ALT, AST, TBIL, ALB, BUN, CR, D-Dimer, PT, APTT, FIB, F VIIIC, CK-MB, CK, and LDH), and ventilation status were collected. The organ functions of these severe COVID-19 patients were assessed by comparing the differences between the two groups.RESULTS:
AST, BUN, CR, CK-MB, LDH, and CK in the non-survival group were higher than those in the survival group, and the differences were statistically significant (P < 0.05). D-Dimer, PT, FIB, and F VIIIC in the non-survival group were higher than the values observed in the survival group, and the differences were statistically significant (P < 0.05). PLT, AST, BUN, CR, D-Dimer, PT, FIB, F VIIIC, CK-MB, CK, and LDH predicted the area under the ROC curve (AUC) of the COVID19 endpoint events and were 0.721, 0.854, 0.867, 0.757, 0.699, 0.679, 0.715, 0.811, 0.935, and 0.802, respectively.CONCLUSION:
The results showed that there were different degrees of damage to the liver, kidneys, blood coagulation, and heart function in the non-survival group. In addition, PLT, AST, BUN, CR, D-Dimer, PT, FIB, F VIIIC, CK-MB, CK, and LDH had value in evaluating disease prognosis
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Coleções:
Bases de dados nacionais
/
Espanha
Base de dados:
IBECS
Assunto principal:
Pneumonia Viral
/
Índice de Gravidade de Doença
/
Taxa de Sobrevida
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Infecções por Coronavirus
/
Betacoronavirus
Limite:
Idoso
/
Feminino
/
Humanos
/
Masculino
Idioma:
Inglês
Revista:
Med. clín (Ed. impr.)
Ano de publicação:
2020
Tipo de documento:
Artigo
Instituição/País de afiliação:
Children' Hospital of Nanjing Medical University/China
/
E Dong Medical Group Huangshi Central Hospital/China
/
Huangshi Hospital of TCM(Infectious Disease Hospital)/China