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Risk factors for recurrence beyond Milan criteria after radiofrequency ablation in transplantable small hepatocellular carcinoma
Chu, Weike; Wu, Xue; Zhang, Peng; Zhou, Hui; Niu, Bin; Li, Ping.
Afiliação
  • Chu, Weike; Tianjin Medical University. Tianjin. China
  • Wu, Xue; Tianjin Medical University. Tianjin. China
  • Zhang, Peng; Tianjin Medical University. Tianjin. China
  • Zhou, Hui; Tianjin Medical University. Tianjin. China
  • Niu, Bin; Tianjin Medical University. Tianjin. China
  • Li, Ping; Tianjin Second People’s Hospital. Tianjin. China
Rev. esp. enferm. dig ; 114(10): 580-585, octubre 2022. tab, graf
Artigo em Inglês | IBECS | ID: ibc-210772
Biblioteca responsável: ES1.1
Localização: ES15.1 - BNCS
ABSTRACT
Background and

objectives:

this study aimed to determine the risk factors of recurrence beyond Milan criteria inpatients with transplantable early hepatocellular carcinoma(HCC) after the first radiofrequency ablation (RFA).Materials and

methods:

a total of 95 patients with newlydiagnosed transplantable small HCC with single lesions≤ 3 cm were analyzed retrospectively.

Results:

during the 39-month median follow-up period, 12(21.8 %) patients with HCC < 2 cm and 22 (56.4 %) patientswith HCC ≥ 2 cm relapsed beyond Milan criteria (p = 0.001).The 1- and 3-year recurrence rates beyond Milan criteriawere 6.3 % and 14.7 % in the HCC < 2 cm group, comparedwith 24.1 % and 55.6 % in the HCC ≥ 2 cm group (p < 0.0001).HCC ≥ 2 cm, red blood cell distribution width-to-lymphocyte ratio (RLR) ≥ 18.3, alpha-fetoprotein (AFP) > 15 ng/ml,and early recurrence after RFA were independent predictorsof recurrence exceeding Milan criteria.

Conclusions:

close follow-up and early liver transplantationshould be initiated to obtain the best survival benefit forpatients with transplantable early, single, small HCC witha tumor diameter ≥ 2 cm and higher RLR and AFP levelsbefore the first RFA and early recurrence after RFA (recurrence within 2 years). (AU)
Assuntos

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Coleções: Bases de dados nacionais / Espanha Base de dados: IBECS Assunto principal: Resultado do Tratamento / Carcinoma Hepatocelular / Ablação por Radiofrequência / Neoplasias Hepáticas / Recidiva Local de Neoplasia Limite: Humanos Idioma: Inglês Revista: Rev. esp. enferm. dig Ano de publicação: 2022 Tipo de documento: Artigo Instituição/País de afiliação: Tianjin Medical University/China / Tianjin Second People’s Hospital/China
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Coleções: Bases de dados nacionais / Espanha Base de dados: IBECS Assunto principal: Resultado do Tratamento / Carcinoma Hepatocelular / Ablação por Radiofrequência / Neoplasias Hepáticas / Recidiva Local de Neoplasia Limite: Humanos Idioma: Inglês Revista: Rev. esp. enferm. dig Ano de publicação: 2022 Tipo de documento: Artigo Instituição/País de afiliação: Tianjin Medical University/China / Tianjin Second People’s Hospital/China
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