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Adverse reactions to the injection of face and neck aesthetic filling materials: a systematic review
Machado, Renato Assis; Oliveira, Lilianny Querino Rocha de; Martelli-Júnior, Hercílio; Pires, Fábio Ramoa; Carvas, Janaína Badin; Rogerio, Victor Edson; Rabelo, Viviane de Azevedo; Coletta, Ricardo D.
Afiliação
  • Machado, Renato Assis; University of Campinas (FOP/UNICAMP). University of São Paulo. University of Campinas. Piracicaba. Brazil
  • Oliveira, Lilianny Querino Rocha de; University of Campinas. School of Dentistry. Piracicaba. Brazil
  • Martelli-Júnior, Hercílio; State University of Montes Claros (UNIMONTES). Dental School. University of José Rosario Vellano (UNIFENAS). Montes Claros. Brazil
  • Pires, Fábio Ramoa; Rio de Janeiro State University. Dental School. Estácio de Sá University. Rio de Janeiro. Brazil
  • Carvas, Janaína Badin; Orofacial Institute of the Americas (IOA). São Paulo. Brazil
  • Rogerio, Victor Edson; Orofacial Institute of the Americas (IOA). São Paulo. Brazil
  • Rabelo, Viviane de Azevedo; Orofacial Institute of the Americas (IOA). São Paulo. Brazil
  • Coletta, Ricardo D; University of Campinas (FOP/UNICAMP). School of Dentistry. University of Campinas. Piracicaba. Brazil
Med. oral patol. oral cir. bucal (Internet) ; 28(3): e278-e284, may. 2023. ilus, tab
Artigo em Inglês | IBECS | ID: ibc-220066
Biblioteca responsável: ES1.1
Localização: ES15.1 - BNCS
ABSTRACT

Background:

Adverse reactions, caused during the inflammation and healing process, or even later, can be induced by the injection of dermal filler and can present a variety of clinical and histological characteristics. In this study we aimed to review the adverse reactions associated with the injection of aesthetic filling materials in the face and neck. Material and

methods:

The review was reported according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses checklist. Studies published that mentioned adverse reactions in patients with aesthetic filling materials in the face or neck were included. Risk of bias was assessed using the Joanna Briggs Institute appraisal tool. After a 2-step selection process, 74 studies were included 51 case reports, 18 serial cases, and five cohorts.

Results:

A total of 303 patients from 20 countries were assessed. Lesions were more prevalent in the lip (18%), nasolabial folds (13%), cheeks (13%), chin (10%), submental (8%), glabella (7%), and forehead (6%). Histopathological analysis revealed a foreign body granuloma in 87.1% of the patients, 3% inflammatory granuloma, 3% lipogranuloma, 2.3% xanthelasma-like reaction, 1% fibrotic reaction, 0.7% amorphous tissues, 0.7% xanthelasma, 0.3% sclerosing lipogranuloma, 0.3% siliconoma, and 0.3% foreign body granuloma with scleromyxedema. In addition, two patients displayed keratoacanthoma and two others displayed sarcoidosis after cutaneous filling. The most commonly used materials were silicone fillers (19.7%), hyaluronic acid (15.5%), and hydroxyethyl methacrylate/ethyl methacrylate suspended in hyaluronic acid acrylic hydrogel (5.6%). All patients were treated, and only 12 had prolonged complications. (AU)
Assuntos


Texto completo: Disponível Coleções: Bases de dados nacionais / Espanha Base de dados: IBECS Assunto principal: Granuloma de Corpo Estranho / Técnicas Cosméticas Limite: Humanos Idioma: Inglês Revista: Med. oral patol. oral cir. bucal (Internet) Ano de publicação: 2023 Tipo de documento: Artigo Instituição/País de afiliação: Orofacial Institute of the Americas (IOA)/Brazil / Rio de Janeiro State University/Brazil / State University of Montes Claros (UNIMONTES)/Brazil / UNICAMP)+Brazil / University of Campinas/Brazil

Texto completo: Disponível Coleções: Bases de dados nacionais / Espanha Base de dados: IBECS Assunto principal: Granuloma de Corpo Estranho / Técnicas Cosméticas Limite: Humanos Idioma: Inglês Revista: Med. oral patol. oral cir. bucal (Internet) Ano de publicação: 2023 Tipo de documento: Artigo Instituição/País de afiliação: Orofacial Institute of the Americas (IOA)/Brazil / Rio de Janeiro State University/Brazil / State University of Montes Claros (UNIMONTES)/Brazil / UNICAMP)+Brazil / University of Campinas/Brazil
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