Poliposis gástrica secundaria a tratamiento con inhibidores de la bomba de protones / Gastric polyposis due to treatment with proton pump inhibitors

RESUMEN

Los pólipos de glándulas fúndicas pueden aparecer en formas esporádicas o asociados a síndrome de poliposis adenomatosa familiar. Se ha descrito su asociación al tratamiento continuado con inhibidores de la bomba de protones (IBP), así como una regresión tras su retirada. No suelen asociar componente displásico.Se describen 4 casos de pacientes en tratamiento crónico con IBP, con endoscopia previa normal, en los que se detectó la presencia de múltiples pólipos de glándulas fúndicas, y se constató su desaparición a los 6 meses tras la supresión del tratamiento(AU)

ABSTRACT

Fundic gland polyps can appear sporadically or in association with familial adenomatous polyposis syndrome. An association between fundic gland polyps and prolonged treatment with proton pump inhibitors has been described, as has their regression after withdrawal of these inhibitors. Dysplastic components are not usually associated.We describe four patients who were receiving chronic treatment with proton pump inhibitors. The results of prior endoscopic analysis were normal. The presence of multiple fundic gland polyps was detected as was their disappearance 6 months after treatment cessation(AU)