Your browser doesn't support javascript.
loading
Saccharomyces cerevisiae Rds2 transcription factor involvement in cell wall composition and architecture
Moreno, Inmaculada; Tutrone, Nunzia; Sentandreu, Rafael; Valentín, Eulogio.
Afiliação
  • Moreno, Inmaculada; University of Valencia. Faculty of Pharmacy. Department of Microbiology and Ecology. Valencia. España
  • Tutrone, Nunzia; University of Valencia. Faculty of Pharmacy. Department of Microbiology and Ecology. Valencia. España
  • Sentandreu, Rafael; University of Valencia. Faculty of Pharmacy. Department of Microbiology and Ecology. Valencia. España
  • Valentín, Eulogio; University of Valencia. Faculty of Pharmacy. Department of Microbiology and Ecology. Valencia. España
Int. microbiol ; 11(1): 57-63, mar. 2008. ilus, tab
Artigo em En | IBECS | ID: ibc-67267
Biblioteca responsável: ES15.1
Localização: ES15.1 - BNCS
ABSTRACT
Although the cell wall is very important in yeasts, relatively little is known about the relationship between its structure and function. In Saccharomyces cerevisiae, a family of 55 transcription factor proteins unique to fungi, so-called zinc cluster proteins, has been described. Of these, Rds2 has been identified as an activator/inhibitor of gluconeogenesis. However, previous studies have pointed out additional roles for this protein, specifically, in the modulation of cell-wall architecture and drug sensitivity. In this work, evidence regarding the role of Rds2 as a regulator of cell-wall architecture and composition is presented based on phenotypical analysis of the cell walls prepared from a S. cerevisiae Rds2 mutant strain. Analyses of the sensitivity of this rds2Delta mutant to different drugs and to osmotic stress showed that Rds2 is indeed involved in the drug-sensitivity response and plays a role in determining osmotic sensitivity (AU)
RESUMEN
No disponible
Assuntos
Buscar no Google
Coleções: Bases de dados nacionais / Espanha Base de dados: IBECS Assunto principal: Saccharomyces cerevisiae / Fatores de Transcrição Tipo de estudo: Estudo prognóstico Idioma: Inglês Revista: Int. microbiol Ano de publicação: 2008 Tipo de documento: Artigo Instituição/País de afiliação: University of Valencia/España
Buscar no Google
Coleções: Bases de dados nacionais / Espanha Base de dados: IBECS Assunto principal: Saccharomyces cerevisiae / Fatores de Transcrição Tipo de estudo: Estudo prognóstico Idioma: Inglês Revista: Int. microbiol Ano de publicação: 2008 Tipo de documento: Artigo Instituição/País de afiliação: University of Valencia/España
...